NAICS 5417

Scientific Research & Development Services

Scientific research and development services (NAICS 5417): Basic and applied research, drug discovery, biotechnology, contract R&D, and technology development services driving US competitiveness.

Industry at a Glance

Sector-wide aggregates across all businesses classified under NAICS 5417 (2017 classification frame). For specific sub-industries within this sector, see the individual reports below.

Employment
1.0M
US Census CBP · 2023 · NAICS 2017
Establishments
22K
US Census CBP · 2023 · NAICS 2017
Annual Payroll
$154.1B
US Census CBP · 2023 · NAICS 2017
Avg Annual Wage
$153,460
Derived from US Census CBP · 2023 · NAICS 2017
Market Size
$340.5B
US Census Economic Census · 2022 · NAICS 2017

Industry Overview

Scientific research and development services (NAICS 5417) encompasses establishments primarily engaged in conducting original investigation undertaken on a systematic basis to gain new scientific or technical knowledge, as well as applying research findings to develop new or improved products and processes. This industry group includes basic research, applied research, and experimental development activities conducted by both public and private institutions, ranging from pharmaceutical and biotechnology research to materials science, nanotechnology, and environmental studies. As a driver of technological advancement, this sector strengthens economic competitiveness, supports breakthrough discoveries, and generates intellectual property that fuels commercialization across virtually every other industry. The sector is characterized by high capital intensity, significant personnel investment in highly educated scientists and engineers, and long development timelines from conception to marketable outcomes.

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Industry Trends

CRO

Accelerating growth in contract research organization (CRO) services as pharmaceutical and biotechnology companies increasingly outsource R&D activities to specialized service providers for cost efficiency and specialized expertise.

02

Expanding investment in artificial intelligence and machine learning applications for drug discovery, materials modeling, and research data analysis, reshaping traditional research methodologies and accelerating development cycles.

03

Rising demand for research services in sustainable technologies, clean energy, and climate adaptation as government policies and corporate sustainability commitments drive funding toward environmental and green chemistry research.

R&D

Increased collaboration between private sector R&D services and academic institutions, facilitated by technology transfer offices and partnerships that commercialize university research discoveries.

R&D

Growing regulatory complexity and compliance requirements driving demand for specialized R&D services in regulatory consulting, clinical trial management, and quality assurance alongside traditional scientific research.

Frequently Asked Questions

What is NAICS 5417? ▾
NAICS 5417 is the classification for establishments engaged in scientific research and development services, encompassing both basic research aimed at advancing scientific knowledge and applied research designed to develop practical applications. This includes activities such as pharmaceutical research, biotechnology development, materials testing, environmental research, and experimental development across physical, life, and engineering sciences. The industry serves as a bridge between scientific discovery and commercialization, enabling technological advancement across all economic sectors.
What types of organizations operate in this industry? ▾
The industry includes independent research institutes, contract research organizations (CROs), pharmaceutical and biotech R&D divisions, materials testing laboratories, environmental research firms, and research centers operated by universities and government agencies. Organizations range from small specialized boutique firms focusing on niche research areas to large multinational corporations with substantial R&D budgets and diverse research portfolios spanning multiple scientific disciplines.
How do R&D services companies generate revenue? ▾
Revenue is generated through multiple channels including government research grants and contracts (particularly from federal agencies like NIH, NSF, and DOE), sponsored research agreements with pharmaceutical and industrial companies, licensing of intellectual property and patents, contract research services on a fee-for-service basis, and milestone-based payments from commercialization partnerships. Funding models vary significantly based on organization type, with academic research centers relying heavily on government funding while private CROs depend primarily on corporate client contracts.
What is the difference between basic research and applied research in this industry? ▾
Basic research, also called fundamental research, is conducted to advance scientific knowledge without immediate commercial application, often exploring fundamental scientific principles and phenomena. Applied research uses existing scientific knowledge to develop practical approaches and new products or processes for specific commercial or industrial purposes. While basic research generates the foundational knowledge, applied research translates these discoveries into viable technologies and products that can be commercialized and brought to market.
How does intellectual property factor into R&D services? ▾
Intellectual property is central to the industry's value creation, with patents, trade secrets, and proprietary methodologies representing significant assets developed through research activities. R&D service providers must carefully manage IP ownership agreements with clients through licensing arrangements and work-for-hire contracts, while also protecting their own proprietary platforms and techniques. Many firms generate substantial revenue through patent licensing and technology transfer agreements that allow commercialization partners to use developed intellectual property.

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